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Concept of Center: Collaboration
The concept is based on the development of projects supporting the
ongoing research programs of collaborating laboratories. This
strategy leverages the specialized expertise and equipment in proteomics
available at the center, and has the potential for significantly
advancing the research projects of the collaborators.
Quantitative proteomics is a complex technology regardless of the
particular techniques used. Our strategy is to conduct the
proteomics work within the center as comprehensive collaborative
projects. The work done includes a complete package of activities
designed to complete a mutually agreed upon scope of work. Pilot
(exploratory) projects of minimal scope can also be performed. A
typical project includes:
Planning and comprehensive consultation
Training and consultation on sample preparation
Provision of tested and certified reagents and protocols for protein sample preparation
Consultation on experimental design
Publication quality, fully analyzed, validated and interpreted data
Advice about limitations of results
Validation and summarization of results
Consultation on results interpretation
Consultation in higher level systems biology interpretations
Supported for the development of grant proposals including the development of preliminary data
Participation in project meetings
Comprehensive support in preparing data for publication
Support for manuscript revision in response to reviewer comments
Support for revision of grant proposals in response to reviewer comments
Consultation on strategies for validation of results by corroborative methods not involving proteomics methods
The
center maintains expertise and equipment for the many components of
modern proteomics. It is impractical for each collaborating
laboratory to acquire the equipment and skills needed for this
specialized work.
A Proteomics Advisory Committee aids the director in setting policies for the center and in prioritizing activities.
Funding a New Project
Funds for executing the projects are derived from project or program
grants awarded to the collaborating PI or jointly with the Center
Director. These can be existing projects or new projects proposed
with support of the center. In the latter case help with grant
proposals is available from the Center Director. The support and
development of comprehensive shared efforts such as these is a challenge
to modern life science. Potential collaborators should review a paper written by the Executive Board of the Association of Biomolecular Resource Facilities
that deals with these challenges. Ordinarily, the Center Director
is listed under key personnel in such collaborative grants or as
co-investigator, and an appropropriate amount for the work is included
in the proprosal budget.
Interested in beginning a new project?
The first step is to contact the director to discuss your possible
project. Also watch our education and news pages for notices of
seminars and talks that may provide some ideas about how this technology
may be useful in your work.