We have partnered with the Columbia NYSTEM Chemical Probe Synthesis
(CPS) Facility on the Morningside campus of Columbia University. The CPS
facility designs and synthesizes small molecule probes and develops
conjugation chemistry for attachment of molecules to surfaces. The
close collaboration between the CPS and the QPC has resulted in a
highly productive platform for systematic detection of protein targets
of small molecules. Quantitative protein target detection in these
affinity experiments employs all-ion fragmentation, ion-mobility
spectrometry and the use of massively parallel computational and data
mining resources to provide a powerful innovative platform. This
coordinated capability for discovery of protein targets of molecules in
affinity experiments is available to interested researchers.
Please contact the QPC or CPS for further information.